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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.
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PAR-22-102: Investigational New Drug (IND)-enabling and Early-Stage Development of Medications to Treat Alcohol Use disorder and Alcohol-Associated Organ Damage (U43/U44 Clinical Trial Optional)
Release Date: 01-21-2022Open Date: 02-28-2022 Due Dates: Multiple Close Date: 12-05-2024Background Currently, there are only three medications (four formulations) approved by the FDA for the treatment of alcohol use disorder (AUD). The need for additional medications to treat those affected by AUD is urgently needed.In addition,alcohol misuseaffects virtually all tissues and is linked with dysfunction and failure of many organs and systems including the liver, heart, pancreas, lung, ...
STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health -
PAR-22-103: Investigational New Drug (IND)-enabling and Early-Stage Development of Medications to Treat Alcohol Use disorder and Alcohol-Associated Organ Damage (UT1/UT2 Clinical Trial Optional)
Release Date: 01-21-2022Open Date: 02-28-2022 Due Dates: Multiple Close Date: 12-05-2024Background Currently, there are only three medications (four formulations) approved by the FDA for the treatment of alcohol use disorder (AUD). The need for additional medications to treat those affected by AUD is urgently needed.In addition,alcohol misuseaffects virtually all tissues and is linked with dysfunction and failure of many organs and systems including the liver, heart, pancreas, lung, ...
STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health -
RFA-DA-25-049: Solutions to enable diagnosis and treatment of adverse health consequences of non-disordered drug use (R41/R42- Clinical Trial Optional)
Release Date: 06-13-2024Open Date: 11-02-2024Due Date: 12-02-2024Close Date: 12-03-2024Background Non-disordered drug use is defined as using a substance in the past year without meeting two or more Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) diagnostic criteria for a substance use disorder (SUD). Non-disordered drug use can have negative health consequences, including, but not limited to, an increased risk of drug (e.g., opioid, cannabis, synthetic ...
STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health -
RFA-DA-25-050: Solutions to enable diagnosis and treatment of adverse health consequences of non-disordered drug use (R43/R44- Clinical Trial Optional)
Release Date: 06-13-2024Open Date: 11-02-2024Due Date: 12-02-2024Close Date: 12-03-2024Background Non-disordered drug use is defined as using a substance in the past year without meeting two or more Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) diagnostic criteria for a substance use disorder (SUD). Non-disordered drug use can have negative health consequences, including, but not limited to, an increased risk of drug (e.g., opioid, cannabis, synthetic ...
SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health -
A244-P017: xTechScalable AI 2
Release Date: 10-03-2023Open Date: 03-11-2024Due Date: 03-31-2025Close Date: 11-18-2024OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Artificial Intelligence/ Machine Learning; Trusted AI and Autonomy; Advanced Computing and Software; Human-Machine Interfaces OBJECTIVE: Topic 1: Scalable Tools for Automated AI Risk Management and Algorithmic Analysis As the Army deploys Artificial Intelligence (AI) systems, there is an inherent risk that the AI model could fail to perform as expe ...
SBIRPhase I/Phase IIDepartment of DefenseArmy -
A244-027: xTechSpecial Forces
Release Date: 10-03-2023Open Date: 04-30-2024Due Date: 03-31-2025Close Date: 10-21-2024OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Trusted AI and Autonomy; Advanced Computing and Software; Integrated Sensing and Cyber; Microelectronics; Integrated Network Systems-of-Systems; Advanced Materials; Human-Machine Interfaces OBJECTIVE: Topic 1: GPS Denied ATAK Compatible Self Location Application The US Army 1st Special Forces Command (Airborne) is seeking a software solution to obt ...
SBIRPhase I/Phase IIDepartment of DefenseArmy -
8.1: Forests and Related Resources
Release Date: 07-02-2024Open Date: 07-02-2024Due Date: 09-17-2024Close Date: 09-17-2024The Forests and Related Resources topic area aims to address the health, diversity, and productivity of the Nation’s forests and grasslands to meet the needs of present and future generations through the development of environmentally sound approaches to increase productivity of forest lands, improve sustainability of forest resources, and develop value-added materials derived from woody resourc ...
SBIR/STTRPhase IDepartment of AgricultureNational Institute of Food and Agriculture -
8.2: Plant Production and Protection (Biology)
Release Date: 07-02-2024Open Date: 07-02-2024Due Date: 09-17-2024Close Date: 09-17-2024The Plant Production and Protection (Biology) topic area will support research to examine novel ways of enhancing crop production and protection by developing new methods for plant improvement and pest management; new food and non-food crop plants through plant breeding; diagnostic technologies for plant diseases; plant characteristics that reduce the harmful impact of plant pests, biotic, and abi ...
SBIR/STTRPhase IDepartment of AgricultureNational Institute of Food and Agriculture -
8.3: Animal Production and Protection
Release Date: 07-02-2024Open Date: 07-02-2024Due Date: 09-17-2024Close Date: 09-17-2024The Animal Production and Protection topic area aims to support the development of innovative, marketable technologies that will provide significant benefit to the production and protection of agricultural animals. New technologies for rapid detection, point-of-care, treatment, and prevention of disease are needed to improve productivity and enhance the biosecurity of our herds and flocks. Better ...
SBIR/STTRPhase IDepartment of AgricultureNational Institute of Food and Agriculture -
8.4: Conservation of Natural Resources
Release Date: 07-02-2024Open Date: 07-02-2024Due Date: 09-17-2024Close Date: 09-17-2024The goal of the Conservation of Natural Resources topic area is to commercialize innovative technologies that are developed with the purpose to conserve, monitor, improve, and/or protect the quality and/or quantity of natural resources and reduce potential waste streams while sustaining climate-smart, optimal farm and forest productivity and profitability. The objective of this topic area is the c ...
SBIR/STTRPhase IDepartment of AgricultureNational Institute of Food and Agriculture